Drug intelligence / Profile preview

Oral insulin

Development stage
Phase 3
Lead developer
Profil
Modality
Recombinant Proteins and Enzymes, Small Molecules
Administration
Oral
01

Overview

Oral insulin is an investigational pharmaceutical drug formulated as an oral capsule containing insulin (150 U) and 200 mg of 4-CNAB (N-(4-chlorosalicyloyl)-4-aminobutyrate). Developed by Profil Institut für Stoffwechselforschung GmbH, this formulation aims to provide an oral alternative to subcutaneous insulin injections for patients with type 2 diabetes. The inclusion of 4-CNAB, a permeation enhancer, is crucial for facilitating the absorption of insulin through the gastrointestinal tract, thereby enabling oral delivery.

02

Targets

INSR (Insulin receptor)

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