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Oral Peste des Petites Ruminants Vaccine
- Development stage
- Preclinical
- Lead developer
- US Biologic
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Vaccines & Immunotherapeutics
- Administration
- Oral
01
Overview
The Oral Peste des Petites Ruminants (PPR) Vaccine is a preclinical veterinary vaccine being developed by US Biologic in collaboration with the University of Edinburgh. It is designed to protect goats and other small ruminants from the Peste des Petites Ruminants virus (PPRV). The vaccine utilizes the OrisBio platform, which employs *Bacillus subtilis* spores as a delivery vehicle to express PPRV antigens. This oral delivery system is intended to provide a stable, heat-resistant, and easy-to-administer alternative to traditional injectable vaccines, which is particularly beneficial for use in remote or resource-limited regions where PPR is endemic. The spores are designed to survive the gastrointestinal environment and induce a protective immune response in the host.
- Other names
- PPR VaccineOral PPR VaccineUS Biologic PPR Vaccine
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