Drug intelligence / Profile preview

oral rehydration salts (III)

Development stage
Unknown
Lead developer
Shandong Dyne Marine Organism Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Oral Rehydration Salts Powder (III) (also known as Oral Rehydration Salts (III)) is an approved oral pharmaceutical product developed and manufactured by Shandong Dyne Marine Organism Pharmaceutical, among other manufacturers. It is a low-osmolarity oral rehydration salts (ORS) formulation designed in accordance with the World Health Organization (WHO) and UNICEF recommendations. The formulation consists of a precise mixture of sodium chloride, anhydrous glucose, potassium chloride, and sodium citrate. It is indicated for the prevention and treatment of mild-to-moderate dehydration and electrolyte loss resulting from acute diarrhea, vomiting, or other fluid-depleting conditions, particularly in pediatric populations. The therapeutic efficacy of the formulation relies on the sodium-glucose cotransporter 1 (SGLT1) in the intestinal mucosa, where the active co-transport of sodium and glucose creates an osmotic gradient that drives the passive absorption of water and essential electrolytes back into the systemic circulation.

Brand names
BoyeKefuleZuomei佐美博叶科复乐
Other names
low-osmolarity ORSlow-osmolarity oral rehydration saltsoral rehydration saltsoral rehydration salts (III)oral rehydration salts powder (III)reduced-osmolarity ORSreduced-osmolarity oral rehydration salts口服补液盐(III)口服补液盐散(III)口服补液盐散(III)口服补液盐(III)
02

Targets

NHE3 (Sodium/hydrogen exchanger 3)SLC5A1 (Sodium Glucose Cotransporter 1)

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