Drug intelligence / Profile preview

Oral sulfate tablet

Development stage
Unknown
Lead developer
Braintree
Modality
Small Molecules
Administration
Oral
01

Overview

Oral sulfate tablets (OST) are a combination osmotic laxative used for bowel cleansing prior to colonoscopy. The formulation typically contains sodium sulfate, potassium sulfate, and magnesium sulfate. These poorly absorbed salts create an osmotic gradient that draws water into the intestinal lumen, increasing stool volume and stimulating peristalsis to clear the colon. In the context of Taejoon Pharmaceutical's clinical development, "conventional OST" refers to their standard tablet formulation (marketed as Orafic in South Korea) used as an active comparator for newer, potentially more convenient bowel prep regimens like CTP0302 (Mini S-OST).

Brand names
Orafic
Other names
Conventional OSTOST

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