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Oral sulfate tablets (OST) are a combination osmotic laxative used for bowel cleansing prior to colonoscopy. The formulation typically contains sodium sulfate, potassium sulfate, and magnesium sulfate. These poorly absorbed salts create an osmotic gradient that draws water into the intestinal lumen, increasing stool volume and stimulating peristalsis to clear the colon. In the context of Taejoon Pharmaceutical's clinical development, "conventional OST" refers to their standard tablet formulation (marketed as Orafic in South Korea) used as an active comparator for newer, potentially more convenient bowel prep regimens like CTP0302 (Mini S-OST).
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