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origanum majorana organic extract
- Development stage
- Preclinical
- Lead developer
- Florida International University
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral, Topical
01
Overview
Origanum majorana organic extract (OME) is a botanical extract derived from *Origanum majorana* (marjoram), a perennial herb widely used as a culinary spice. Developed by researchers at Florida International University, OME is being investigated for its potential antineoplastic activity, particularly in breast cancer. Preclinical studies indicate that OME inhibits the proliferation of breast cancer cells (such as MCF-7 and MDA-MB-231) by disrupting mitochondrial bioenergetics, reducing ATP production, and inducing senescence, apoptosis, and autophagic cell death.
- Other names
- OMEmarjoram organic extractoriganum majorana extract
02
Targets
EGFR T790M (Epidermal growth factor receptor T790M mutant)CYP1A2 (Cytochrome P450 1A2)
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