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ORM-12471 is a small molecule drug candidate developed as an antagonist of the alpha-2C adrenergic receptor (ADRA2C). Its primary mechanism of action is to block the ADRA2C receptor, which plays a role in vasoconstriction and vascular tone. ORM-12471 has been investigated for the prevention of cold-induced vasospasm, particularly in conditions such as Raynaud's phenomenon. The drug was developed by Orion Corporation[1][4].
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