Drug intelligence / Profile preview

ormutivimab

Development stage
Phase 2
Lead developer
North China Pharmaceutical
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intramuscular, Subcutaneous, Infiltration
01

Overview

Ormutivimab is a recombinant human anti-rabies monoclonal antibody developed for post-exposure prophylaxis of rabies. It functions by providing passive immunity against the rabies virus, neutralizing the virus particles, and preventing their attachment to and penetration into host cells. This offers immediate protection during the critical period before the body's immune system can mount an active response from a rabies vaccine. Ormutivimab is being developed as a safer alternative to plasma-derived Human Rabies Immune Globulin (HRIG), aiming to mitigate risks associated with serum allergic reactions and blood-transmitted infectious diseases.

Brand names
ormutivimab
Other names
recombinant human anti-rabies monoclonal antibody NM57 injection
02

Targets

RABV-G (Rabies virus glycoprotein)

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