ornithine alpha ketoglutarate

Ornithine alpha ketoglutarate (OKG) is a salt formed from the amino acid ornithine and alpha-ketoglutarate, a precursor to glutamine. It is used as a dietary supplement and in clinical nutrition, particularly for wound healing, burns, trauma recovery, and muscle protein synthesis. OKG may alter amino acid metabolism in the body and stimulate anabolic hormone secretion (notably insulin and growth hormone), which can promote protein synthesis and reduce muscle catabolism. Its mechanism of action is not fully understood but involves increased production of metabolites such as glutamine, polyamines, arginine, and ketoacids. OKG has been administered both orally and intravenously in various clinical settings[1][2][3][6][7].

Other names

ornithine ketoglutarate2-Oxopentanedioic Acid L-Ornithine