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Ortho-phthalaldehyde (OPA) is a high-level disinfectant used primarily for the sterilization of heat-sensitive medical and dental instruments, such as endoscopes. Developed as a more stable and less irritating alternative to glutaraldehyde, OPA exerts its antimicrobial effect by reacting with the primary amino groups of microbial proteins, leading to protein cross-linking and the subsequent inactivation of bacteria, mycobacteria, viruses, and fungi. Garonit Pharmaceutical lists OPA as part of its chemical and cosmetic ingredient portfolio, highlighting its utility in industrial and medical applications rather than as a systemic therapeutic candidate.
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