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OrthodontiCell
- Development stage
- Unknown
- Lead developer
- Leonhardt Ventures
- Modality
- Cell Therapies, Device-based Delivery → Drug Delivery Systems
- Administration
- Oral
01
Overview
OrthodontiCell is a regenerative medicine platform developed by Leonhardt Ventures (through its startup OrthodontiCell) designed to accelerate orthodontic tooth movement and enhance dental bone remodeling. The therapy utilizes a combination of bioelectronic stimulation and a proprietary biologic composition. The bioelectronic component is engineered to non-invasively modulate the expression of specific signaling proteins, such as RANKL (Receptor Activator of Nuclear Factor kappa-B Ligand) and OPG (Osteoprotegerin), which are essential for the bone resorption and formation processes required for tooth displacement. This is integrated with the delivery of a cell therapy component, typically involving mesenchymal stem cells or other regenerative biologics, to facilitate faster dental alignment and improve the stability of the results.
- Brand names
- OrthodontiCell
- Other names
- OrthodontiCell-Leonhardt Ventures
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