Drug intelligence / Profile preview

orthosiphonis folium extract

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Orthosiphonis folium extract is a standardized herbal preparation derived from the dried leaves and stem tips of *Orthosiphon stamineus* (also known as *Orthosiphon aristatus*). Recognized in the European Pharmacopoeia, the extract contains a complex mixture of active constituents, including lipophilic flavones such as sinensetin, eupatorin, and scutellarein, as well as rosmarinic acid and various triterpenes. It is primarily utilized for its diuretic, anti-inflammatory, and antimicrobial properties, specifically for the irrigation of the urinary tract in cases of bacterial infections, inflammatory diseases, and kidney gravel. The diuretic mechanism involves enhanced ion excretion, which has been compared to the action of loop diuretics like furosemide. Beyond its primary urological indications, traditional uses include the management of hypertension, diabetes, and hyperlipidemia.

Brand names
Java teaCat's beard
Other names
Orthosiphon stamineus leaf extractOrthosiphon aristatus leaf extractFolium OrthosiphonisJava tea extractCat's whiskers extractCat's beard extract
02

Targets

ADORA1 (Adenosine receptor A1 subtype)COX

Beyond the preview

Go deeper on orthosiphonis folium extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on orthosiphonis folium extract.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call