Drug intelligence / Profile preview

OS-1

Development stage
Phase 2
Lead developer
Otsuka Pharmaceutical Factory, Inc.
Modality
Small Molecules
Administration
Oral
01

Overview

OS-1 is an oral rehydration solution (ORS) developed by Otsuka Pharmaceutical Factory, specifically formulated for the dietary management of dehydration. It is designed based on the physiological principles of the sodium-glucose cotransport system in the small intestine, which remains functional even during diarrheal illness. By providing a precise balance of electrolytes (sodium, potassium, chloride, and magnesium) and carbohydrates (glucose), OS-1 facilitates the rapid and efficient absorption of water and essential salts into the bloodstream. It is primarily indicated for patients suffering from mild-to-moderate dehydration caused by infectious enteritis, diarrhea, vomiting, high fever, or heatstroke, and is also used for fluid maintenance in elderly patients or those with inadequate oral intake. In Japan, it is classified as a Food for Special Dietary Use (Medical Food) and is a standard clinical recommendation for rehydration therapy.

Brand names
OS-1OS1OS 1OS-1 JellyOS1 JellyOS 1 Jelly
Other names
Oral Rehydration Solution OS-1
02

Targets

SLC superfamily (Solute carrier superfamily)

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