Drug intelligence / Profile preview

osmanthus fragrans water extract

Development stage
Unknown
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical, Inhalation
01

Overview

**Osmanthus fragrans water extract** is a botanical water extract prepared from the flowers of *Osmanthus fragrans*, a traditional Chinese medicinal and functional food plant in the Oleaceae family. It is a complex natural-product mixture rather than a single defined molecular entity, reported to contain constituents such as acteoside, polyphenols, flavonoids, and tannins. Preclinical studies have investigated this extract for anti-melanogenic, antioxidant, anti-inflammatory, antiproliferative, and anti-muscle-atrophy effects, with proposed activity involving modulation of the MITF-tyrosinase melanogenesis pathway and stimulation of PI3K-Akt signaling in muscle models. There is no clear evidence from the provided context that this extract has been developed as a branded pharmaceutical product, entered formal clinical development, or received regulatory approval.

Other names
Osmanthus fragrans water extractOFWEOsmanthus fragrans flower water extractOF-F-W
02

Targets

TYR (Tyrosinase)MITF (Melanocyte inducing transcription factor)

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