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OSTA27 is a novel antibiotic candidate developed by Osta Therapeutics, designed to address the growing issue of antibiotic resistance. It utilizes the proprietary OSTA (On-Site-Target-Activated) approach, which acts as a triggerable drug delivery system activated by pathogens themselves. This mechanism allows for targeted delivery and activation of active pharmaceutical ingredients specifically at the site of infection, minimizing off-target effects and reducing the risk of resistance development. The lead indication for OSTA27 is Carbapenem-resistant Acinetobacter baumannii (CRAb) infections[1].
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