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OsteoActivator-P
- Development stage
- Discontinued
- Lead developer
- Osteo Pharma
- Modality
- Small Molecules
- Administration
- Implant
01
Overview
**OsteoActivator-P** is an investigational, drug-eluting guided-bone-regeneration medical device developed by Osteo-Pharma for localized alveolar ridge preservation after dental extraction. It consists of a porcine pericard collagen barrier membrane with a biodegradable PLGA coating that provides sustained local delivery of **testosterone** and **alendronate**. Testosterone is intended to stimulate osteoblast-mediated bone formation, while alendronate inhibits osteoclast-mediated bone resorption, with the combined local effect intended to accelerate formation of high-quality bone and enable earlier dental implant placement. OsteoActivator-P entered a randomized prospective clinical study in the Netherlands comparing the coated membrane with an uncoated collagen membrane. ([osteo-pharma.com](https://www.osteo-pharma.com/technology-platform/))
- Other names
- OsteoActivator-P
02
Targets
AR (Adrenergic receptors)FDPS (Farnesyl pyrophosphate synthase)
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