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OsteoCure
- Development stage
- Preclinical
- Lead developer
- OsteoCure Therapeutics
- Modality
- Small Molecules, Hydrogel Systems → Drug Delivery Systems
- Administration
- Injection
01
Overview
OsteoCure (brand name OCTA1) is a small molecule drug-device combination being developed by OsteoCure Therapeutics, a spinout from Duke University. The product consists of the active ingredient adenosine delivered via a proprietary injectable scaffold containing adenosine-loaded microgels. This delivery system is designed for localized, sustained release at the site of orthopedic injury to modulate inflammation, stimulate osteogenesis (bone formation), and provide opioid-sparing pain relief. OsteoCure is currently in preclinical development for the treatment of orthopedic conditions including bone fractures, spinal fusions, orthopedic trauma, and osteoporosis.
- Brand names
- OCTA1OCTA-1OCTA 1
- Other names
- adenosine
02
Targets
ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)ADORA2B (Adenosine A2B receptor)ADORA3 (Adenosine A3 receptor)
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