Drug intelligence / Profile preview

Osteogrow-C

Development stage
Unknown
Lead developer
Genera Research
Modality
Recombinant Proteins and Enzymes
Administration
Implant
01

Overview

**Osteogrow-C** is a personalized, locally implanted osteoinductive biologic-device combination developed by Genera Research for bone fracture nonunion. It contains recombinant human bone morphogenetic protein 6 in an autologous blood coagulum carrier, supplemented with tricalcium phosphate ceramics as a compression-resistant matrix. Locally delivered rhBMP6 activates bone morphogenetic protein receptor signaling to induce osteogenic differentiation and new bone formation, while the ceramic matrix provides mechanical support and osteoconductivity. The product is prepared intraoperatively from the patient's blood and implanted at the surgically stabilized fracture site. ([genera-research.com](https://genera-research.com/product/osteoforunion))

Other names
Osteogrow-C
02

Targets

BMPR1ABMPR2 (Bone morphogenetic protein receptor type II)BMPR (Bone morphogenetic protein receptor)

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