Drug intelligence / Profile preview

OSTEOproSPINE

Development stage: Unknown
Lead developer: Genera Research
Modality: Recombinant Proteins and Enzymes
Administration: Implant

Overview

**OSTEOproSPINE** is a clinical-stage bone-regeneration therapy developed for lumbar spinal fusion in adults with degenerative disc disease. The product, also designated **OSTEOGROW-A**, consists of recombinant human bone morphogenetic protein 6 delivered in autologous peripheral-blood coagulum and reinforced with bone-bank allograft as a compression-resistant osteoconductive matrix. Recombinant BMP6 promotes osteogenesis and vertebral fusion through BMP signaling, with the goal of replacing iliac-crest autograft and avoiding graft-harvest morbidity. Genera Research sponsored a Phase II randomized, blinded PLIF study in 143 patients; the registered study ended on March 13, 2023, with results posted in February 2026. ([genera-research.com](https://www.genera-research.com/product/osteoprospine))

Other names: OSTEOproSPINE

Targets

BMPR (Bone morphogenetic protein receptor)

Beyond the preview

Go deeper on OSTEOproSPINE.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on OSTEOproSPINE.

Explore the full profile