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OSTIVA is a prescription-strength oral nutritional supplement developed by Sciele Pharma (now part of Shionogi) specifically formulated to support bone health in women. The product contains a combination of essential minerals, including calcium and magnesium, alongside vitamins D, B6, B12, and Metafolin (L-methylfolate). OSTIVA is designed to address bone health through two primary pathways: providing the necessary building blocks for bone mineralization and reducing elevated homocysteine levels, which are associated with increased fracture risk and bone fragility. By utilizing Metafolin, the bioactive form of folate, the formulation ensures efficient homocysteine metabolism even in individuals with genetic polymorphisms in the MTHFR enzyme. It is marketed as a prescription product to ensure medical oversight in managing nutritional deficiencies related to skeletal maintenance.
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