Drug intelligence / Profile preview

OTP-3

Development stage
Preclinical
Lead developer
Yunnan Agricultural University
01

Overview

OTP-3: sourced facts only. name: "Mechanistic studies disclosed that OTP-3 directly binds to EGFR extracellular domain decreases EGF and EGFR binding affinities by combination with nimotuzumab." [PMID:35970070]; target: "Mechanistic studies disclosed that OTP-3 directly binds to EGFR extracellular domain decreases EGF and EGFR binding affinities by combination with nimotuzumab." [PMID:35970070]; developer: "Key Laboratory of Pu-er Tea Science, Ministry of Education, Yunnan Agricultural University, Kunming 650201, China; College of Science, Yunnan Agricultural University, Kunming 650201, China." [PMID:35970070]; stage: "Accordingly, OTP-3 combined with nimotuzumab significantly inhibits tumor growth through degrading EGFR in vivo." [PMID:35970070]

02

Targets

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