Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
OVV-00
- Development stage
- Unknown
- Lead developer
- The First Affiliated Hospital of Xinxiang Medical University
- Modality
- Gene Silencing → Gene Therapies, Oncolytic Viruses → Oncolytic Therapeutics, Gene Editing → Gene Therapies, Gene Addition/Replacement → Gene Therapies
- Administration
- Intratumoral
01
Overview
OVV-00 is an investigational oncolytic vaccinia virus (OVV) being developed by The First Affiliated Hospital of Xinxiang Medical University for the treatment of advanced solid tumors. As an oncolytic viral agent, OVV-00 is designed to selectively infect and replicate within malignant cells, leading to direct tumor cell lysis (oncolysis) while sparing healthy tissues. This process releases tumor-associated antigens and pro-inflammatory signals into the tumor microenvironment, which is intended to stimulate a systemic anti-tumor immune response. In clinical development, OVV-00 is being evaluated in combination with VSV-01, an oncolytic vesicular stomatitis virus, administered via multiple intratumoral injections. This dual-virus strategy aims to leverage the distinct immunogenic profiles and mechanisms of both vaccinia and vesicular stomatitis viruses to enhance therapeutic efficacy in patients who have exhausted standard treatment options.
- Other names
- oncolytic vaccinia virus 00
Beyond the preview
Go deeper on OVV-00.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on OVV-00.