Drug intelligence / Profile preview

ox bile extract

Development stage
Phase 2
Lead developer
Titan Biotech
Modality
Small Molecules
Administration
Oral
01

Overview

Ox bile extract is a natural product derived from the bile of cattle, typically processed into a powdered form for stability and ease of use[1][3]. It consists mainly of bile acids (such as cholic acid, chenodeoxycholic acid), cholesterol, bilirubin, and fatty acids[1][3]. Its primary function is to supplement bile acids in individuals with insufficient bile production, thereby supporting fat digestion and the absorption of fat-soluble vitamins (A, D, E, K)[2][5]. Ox bile extract emulsifies dietary fats, facilitating their breakdown by digestive enzymes, and may alleviate symptoms like bloating, indigestion, and fat malabsorption, particularly in those with gallbladder dysfunction, biliary tract disorders, or after gallbladder removal[2][4]. It is also used in traditional medicine and has been explored for potential roles in supporting liver function, regulating cholesterol, and possibly exerting anti-inflammatory effects in the gut[2][5]. Ox bile extract is available as a dietary supplement and is also utilized in the formulation of certain gallbladder medications and in scientific research to study digestive processes[1][3].

Other names
ox bilebovine bile extractox bile powderox bile supplementox bile extract powder
02

Targets

GPBAR1ABCB11 (Bile salt export pump)FXR (Farnesoid x-activated receptor)

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