OX640

OX640 is a powder-based, intranasal epinephrine (adrenaline) rescue medication developed for the acute treatment of severe allergic reactions, including anaphylaxis. It utilizes Orexo’s proprietary AmorphOX drug delivery platform, which enables rapid systemic absorption of epinephrine after nasal administration and offers improved physical and chemical stability compared to traditional injectable formulations. The product is designed as a needle-free alternative to auto-injectors, providing greater convenience, longer shelf life, and more flexible storage conditions. Clinical studies have shown that OX640 achieves clinically relevant plasma levels of epinephrine more rapidly than intramuscular injection products—even in patients with allergic rhinitis—supporting its use as a fast-acting emergency therapy for anaphylaxis[1][3][4][5].