oxaceprol

Oxaceprol is a small molecule anti-inflammatory drug used primarily for the treatment of osteoarthritis and other degenerative or inflammatory joint disorders, including rheumatoid arthritis and inflammation of connective tissues[1][3][4][5]. It is a derivative of the amino acid proline[2]. Oxaceprol acts by inhibiting the accumulation, adhesion, and migration of leukocytes (white blood cells), particularly neutrophils, into inflamed joints or tissues. This mechanism reduces pain, swelling, stiffness, and other symptoms associated with joint inflammation without significantly inhibiting prostaglandin synthesis—a key difference from traditional NSAIDs[1][6]. Oxaceprol has been shown to be well-tolerated with fewer gastrointestinal side effects compared to conventional NSAIDs. It is available in oral formulations such as tablets or capsules and has been widely used in Europe for over 30 years[7].

Brand names

Oxaproct 600Oxaproct600Oxaproct-600

Other names

N-acetyl-L-hydroxyprolineN-acetyl-4-hydroxyprolineN-acetyl4-hydroxyprolineN-acetyl 4-hydroxyprolineN-acetylhydroxyprolineoxaceprolacetyl hydroxyprolineoxaceprol (cis)-isomer