oxidized and regenerated cellulose

Oxidized and regenerated cellulose is a plant-derived bioabsorbable hemostatic agent used in surgical procedures to control capillary, venous, and small arterial bleeding when conventional methods (such as ligation or cautery) are impractical or ineffective. It is produced by the partial oxidation of regenerated cellulose fibers. Upon application to a bleeding site during surgery, it forms a gelatinous mass that acts as a physical matrix for platelet adhesion and clot formation. The low pH of the material also promotes vasoconstriction and inhibits bacterial growth. The product is fully absorbable within several weeks post-implantation with minimal tissue reaction. It does not induce an immune response and can be left in situ after surgery[2][3][4][5][6]. Its primary mechanism of action is physical—providing a scaffold for clot formation—and chemical—lowering local pH to promote hemostasis.

Brand names

SURGICELSurgiGuardOxycelPahacelCuraCelSurgi-ORCTAGUM Regenerated Oxidized Cellulose

Other names

oxidized regenerated celluloseORC