oxidized regenerated cellulose

Oxidized regenerated cellulose (ORC) is an absorbable, synthetic mechanical barrier used to prevent postoperative adhesions and provide hemostasis. It is produced through the controlled oxidation of cellulose, resulting in a material that can be placed between surgical surfaces to physically separate them during the initial stages of wound healing. In a clinical trial conducted by National Taiwan University Hospital, ORC was evaluated for its efficacy in reducing post-thyroidectomy adhesions, which can cause neck discomfort, dysphagia, and skin-to-trachea tethering. The material is typically absorbed by the body within approximately two weeks, minimizing long-term foreign body reactions.

Brand names

SurgicelInterceed

Other names

oxidized cellulosepolyanhydroglucuronic acid