Oxothiazolidinecarboxylic acid

Oxothiazolidinecarboxylic acid (also known as procysteine or OTC) is a small molecule prodrug of cysteine and an antioxidant. It is metabolized intracellularly to cysteine, thereby stimulating glutathione synthesis. This mechanism supports cellular antioxidant defenses by increasing the availability of glutathione, a key endogenous antioxidant. Oxothiazolidinecarboxylic acid has been investigated for its potential therapeutic effects in conditions associated with oxidative stress and glutathione deficiency. Clinical studies have explored its use in HIV infection and vascular calcification due to its ability to replenish intracellular cysteine and maintain glutathione levels[2][3][6]. It has also been used as an ingredient in personal care products due to its safety profile[1][7].

Brand names

Procysteine

Other names

2-oxothiazolidine-4-carboxylic acid(4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid