Drug intelligence / Profile preview

OXS-4235

Development stage
Unknown
Lead developer
GT Biopharma
Modality
Small Molecules
Administration
Oral
01

Overview

OXS-4235 is a small molecule therapeutic candidate developed as a chemical inhibitor of the P62-ZZ domain, targeting the treatment of multiple myeloma and associated osteolytic lesions. It is intended to selectively kill multiple myeloma cells while sparing healthy cells, potentially shrinking tumors and increasing bone density. The drug has shown preclinical activity in vitro and in vivo, demonstrating the ability to kill myeloma cells and decrease osteolytic bone lesions. It was developed by Dr. Sean Xie and is under development by Oxis Biotech, a subsidiary of GT Biopharma (formerly Oxis International)[1][2][3][4][5][6][7][9][13][14].

Other names
Oxis-4235Oxis4235Oxis 4235
02

Targets

SQSTM1 (Sequestosome-1)

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