Drug intelligence / Profile preview

Oxybenzone

Development stage
Phase 1
Modality
Small Molecules
Administration
Topical
01

Overview

Oxybenzone is an organic compound and a derivative of benzophenone, widely used as a sunscreen agent in topical formulations. It functions by absorbing ultraviolet (UV) radiation, particularly UV-A rays, thereby preventing them from penetrating the skin and causing damage such as sunburn or premature aging. Oxybenzone is also used in various cosmetics and personal care products for its photoprotective properties. Its mechanism of action involves ultrafast energy dissipation after UVA irradiation, which helps protect skin cells from UV-induced harm[1][4][8]. The compound has been under scrutiny due to environmental concerns—especially its toxicity to coral reefs—and potential safety issues for humans[6]. Oxybenzone was first synthesized in Germany in the early twentieth century[4].

Brand names
MeijerMilestab 9Milestab9Milestab-9Eusolex 4360Eusolex4360Eusolex-4360Escalol 567Escalol567Escalol-567KAHSCREEN BZ-3
Other names
benzophenone-3benzophenone3benzophenone 3BP-3BP3BP 32-benzoyl-5-methoxyphenol2-hydroxy-4-methoxybenzophenone4-methoxy-2-hydroxybenzophenoneoxibenzonaoxybenzonum

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