oxycodone + acetaminophen

Oxycodone + acetaminophen is a fixed-dose combination oral analgesic used to relieve moderate to severe pain when opioid treatment is necessary and other pain medicines are inadequate or not tolerated. Oxycodone is an opioid analgesic that acts on the central nervous system by binding to opioid receptors, reducing the transmission of pain signals in the brain and spinal cord. Acetaminophen is a non-opioid analgesic and antipyretic that works primarily by inhibiting prostaglandin synthesis in the central nervous system, thereby enhancing the effects of oxycodone. The combination provides synergistic pain relief but carries risks such as dependence, addiction (primarily due to oxycodone), respiratory depression, and potential liver toxicity at high doses or with prolonged use due to acetaminophen[1][3][4][5]. It is available only by prescription.

Brand names

EndocetMagnacetNarvoxPercocetPerloxxPrimalevRoxicetRoxiloxTyloxXartemix XRXoloxoxyCODONE/ACET (Canada)Rivacocet (Canada)Teva-Oxycocet (Canada)

Other names

oxycodone and acetaminophen