Drug intelligence / Profile preview

oxygen-ozone mixture

Development stage
Unknown
Lead developer
INRCA Hospital
Modality
Small Molecules
Administration
Intramuscular, Percutaneous
01

Overview

The oxygen-ozone mixture is a gaseous therapeutic agent composed of medical-grade oxygen and ozone (O3), primarily utilized as a minimally invasive treatment for lumbar pain and intervertebral disc degeneration. Administered via intramuscular-paravertebral or intradiscal injection, the mixture exerts anti-inflammatory and analgesic effects by modulating oxidative stress, inhibiting pro-inflammatory mediators, and reducing nerve irritation associated with discopathy. The therapeutic gas is typically generated on-site using medical ozone generators at concentrations ranging from 10–20 μg/mL of ozone. It has been extensively studied in Western Europe, particularly in Italy, for spinal conditions including disc herniation and chronic low back pain.

Other names
O2-O3 mixtureO-2-O3 mixtureO 2-O3 mixturemedical ozoneoxygen-ozone therapyO3-O2 mixtureO-3-O2 mixtureO 3-O2 mixture
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)IL1A (Interleukin 1 alpha)

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