Drug intelligence / Profile preview

Oxymetholone

Development stage
Unknown
Lead developer
Roche
Modality
Small Molecules
Administration
Oral
01

Overview

Oxymetholone is a synthetic anabolic-androgenic steroid (AAS) and a derivative of dihydrotestosterone. It is primarily indicated for the treatment of anemias caused by deficient red cell production, including acquired and congenital aplastic anemia, myelofibrosis, and hypoplastic anemias due to myelotoxic drugs. Oxymetholone acts mainly by stimulating erythropoiesis through enhancement of erythropoietin production in bone marrow failure syndromes[2][7][8]. Its mechanism involves activation of the androgen receptor, leading to increased protein synthesis and muscle mass. While it was once used for osteoporosis and HIV/AIDS wasting syndrome due to its anabolic effects[5], its use has declined because safer alternatives are available. The drug is known for significant side effects including hepatotoxicity[5][8].

Brand names
Anadrol-50Anadrol50Anadrol 50
Other names
17α-methyl-2-hydroxymethylene-17β-hydroxy-5α-androstan-3-oneAnadrolAnapolon
02

Targets

SHBG (Sex hormone-binding globulin)EGLN1 (Prolyl hydroxylase domain-containing protein 2)AR (Adrenergic receptors)

Beyond the preview

Go deeper on Oxymetholone.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Oxymetholone.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call