oxymorphone

Oxymorphone is a potent opioid analgesic used for the management of moderate to severe pain, particularly in patients who require an opioid and for whom alternative treatments are inadequate. It is available as immediate-release and extended-release oral tablets, as well as injectable formulations. Oxymorphone acts primarily as a selective agonist at the mu-opioid receptor in the central nervous system, altering pain perception and response. At higher doses, it may interact with other opioid receptors. The drug is more lipophilic than morphine, allowing easier penetration of the blood-brain barrier. Oxymorphone has no significant interactions with major cytochrome P450 enzymes (CYP3A4, CYP2C9, CYP2D6), reducing its potential for certain drug-drug interactions[1][2][5][7].

Brand names

OpanaOpana ERNumorphan

Other names

14-hydroxydihydromorphinone