Drug intelligence / Profile preview

Oxyquinoline

Development stage
Unknown
Modality
Small Molecules
Administration
Vaginal, Topical
01

Overview

Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is primarily used as a biocidal component in over-the-counter products to inhibit abnormal biological growth in the vagina and restore natural pH. Oxyquinoline acts as a biocide to eliminate bacteria and fungi; however, its precise mechanism of action remains unknown. It has also been used as a stabilizer for hydrogen peroxide in cosmetic products and serves as a reagent and metal chelator. In pharmaceutical applications, it is found in combination vaginal gels for restoring acidity[1][3][5]. Oxyquinoline is also the ligand component of indium In-111 oxyquinoline (oxine), which is used diagnostically for radiolabeling autologous leukocytes[2][4][6].

Brand names
Fem PhRelagard
Other names
8-hydroxyquinolineoxine
02

Targets

METAP2 (Methionine aminopeptidase 2)

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