oxytocin morpholino antisense

Oxytocin morpholino antisense is an antisense morpholino oligonucleotide designed to selectively inhibit the translation of oxytocin (Oxt) mRNA. Developed primarily as a research tool by researchers at the University of California, Davis, this synthetic oligonucleotide blocks the synthesis of the neuropeptide oxytocin in specific brain regions, such as the paraventricular nucleus (PVN) and the bed nucleus of the stria terminalis (BNST). In preclinical animal models, particularly California mice (*Peromyscus californicus*), localized administration of this morpholino has been utilized to study the distinct roles of specific oxytocin-producing neuronal populations in modulating social behaviors, including social approach, social avoidance, and social vigilance under stress or unstressed conditions.

Other names

oxytocin antisense morpholinooxytocin antisense morpholino oligonucleotideoxytocin morpholinooxytocin morpholino antisenseoxytocin morpholino antisense oligonucleotide