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Drug intelligence / Profile preview
Pabron
- Development stage
- Unknown
- Lead developer
- Taisho Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Pabron is a widely recognized brand of over-the-counter (OTC) cold and cough medications developed and manufactured by Taisho Pharmaceutical Co., Ltd. in Japan. The product line consists of multi-ingredient small molecule combinations designed to provide comprehensive relief for a variety of common cold symptoms, including fever, cough, sputum, sore throat, and nasal congestion. A representative formulation, Pabron Gold A, contains seven active ingredients: acetaminophen (analgesic/antipyretic), dihydrocodeine phosphate (cough suppressant), guaifenesin (expectorant), dl-methylephedrine hydrochloride (bronchodilator), chlorpheniramine maleate (antihistamine), anhydrous caffeine, and riboflavin (vitamin B2). These medications are available in several dosage forms, including tablets and granules, and are among the most popular consumer health products for respiratory ailments in the Japanese market.
- Brand names
- PabronPabron Gold APabron S Gold WPabron Ace Pro
02
Targets
ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)HRH1 (Histamine H1 Receptor)ADRB2 (β2)MOR (Mu opioid receptor)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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