Packed red blood cell transfusion

Packed red blood cell (PRBC) transfusion is a biological intervention used to treat symptomatic anemia by increasing the volume of oxygen-carrying red blood cells in the circulatory system. In the specific context of clinical research conducted by the Jonsson Comprehensive Cancer Center, this intervention is evaluated for managing postoperative anemia in patients undergoing pancreatectomy for pancreatic cancer. The procedure involves the intravenous administration of concentrated erythrocytes to restore hemoglobin levels, thereby mitigating physiological effects such as fatigue and impaired tissue oxygenation. The associated feasibility study specifically compares the impact of restrictive versus liberal transfusion thresholds on patient quality of life and recovery outcomes following major oncological surgery.

Other names

PRBC transfusionRed blood cell transfusionErythrocyte transfusion