Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
paclitaxel (National Cancer Institute)
- Development stage
- Unknown
- Lead developer
- Università degli Studi di Roma Tor Vergata
- Modality
- Small Molecules
- Administration
- Intra-arterial, Intravenous
01
Overview
**Paclitaxel** is a small-molecule taxane microtubule stabilizer. It binds beta-tubulin in polymerized microtubules, promotes microtubule assembly, and prevents depolymerization, disrupting mitotic-spindle dynamics and cell division. In the University of Rome Tor Vergata-sponsored PACUS trial, paclitaxel was evaluated as a locally delivered antiproliferative agent after femoropopliteal angioplasty for critical limb ischemia; catheter-delivered high-intensity, low-frequency ultrasound and temporary flow occlusion were used to enhance arterial-wall uptake. This was a delivery-strategy study of paclitaxel rather than a distinct new molecular entity.
- Brand names
- AnzataxBris TaxolOnxolPaxenePraxelTaxol
- Other names
- paclitaxelPTXTaxol A
02
Targets
TUBB (Tubulin (alpha and beta subunits))
Beyond the preview
Go deeper on paclitaxel (National Cancer Institute).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on paclitaxel (National Cancer Institute).