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paclitaxel + topotecan
- Development stage
- Unknown
- Lead developer
- Bristol Myers Squibb
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
A combination chemotherapy regimen consisting of paclitaxel, a taxane that stabilizes microtubules, and topotecan, a topoisomerase I inhibitor. This combination has shown efficacy in treating various cancers, particularly relapsed or refractory aggressive non-Hodgkin's lymphoma and advanced cervical cancer.
- Other names
- topotecan and paclitaxelpaclitaxel and topotecan
02
Targets
TOP1 (DNA Topoisomerase I)
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