Drug intelligence / Profile preview

Pain Away (Wellnex Life)

Development stage
Unknown
Lead developer
Wellnex Life
Modality
Small Molecules
Administration
Topical
01

Overview

Pain Away is a topical analgesic brand developed and marketed by Wellnex Life, following its acquisition of the brand in 2023. The product line features formulations such as creams, gels, and sprays primarily containing *Arnica montana* extract, often in combination with other natural ingredients like rosemary oil and eucalyptus oil. The therapeutic effect is largely attributed to sesquiterpene lactones, specifically helenalin, which penetrates the skin to exert anti-inflammatory and analgesic actions. The primary mechanism involves the inhibition of the transcription factor NF-κB, which reduces the expression of pro-inflammatory genes and cytokines. It is indicated for the relief of muscular aches, pains, joint inflammation, and bruising associated with sports injuries or chronic conditions like arthritis.

Brand names
Pain Away
Other names
ArnicaArnica montana
02

Targets

NF-κB

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