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Pain-O-Joint
- Development stage
- Unknown
- Lead developer
- HAB Pharmaceuticals & Research
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Pain-O-Joint is a topical analgesic spray developed and manufactured by Hab Pharmaceuticals. It is a combination product containing diclofenac diethylamine, methyl salicylate, menthol, and linseed oil. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby providing anti-inflammatory and analgesic effects. Methyl salicylate and menthol act as counter-irritants, producing a cooling and then warming sensation that distracts from deeper muscle or joint pain. Linseed oil (containing alpha-linolenic acid) may contribute to the anti-inflammatory profile. The spray is indicated for the relief of musculoskeletal pain, including joint pain, backache, and sprains, and is available as an over-the-counter (OTC) product in India.
- Brand names
- Pain-O-Joint
- Other names
- Pain-O-Joint spray
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TRPM8 (Transient receptor potential cation channel subfamily M member 8)PGHS-1 (Prostaglandin G/H Synthase 1)
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