Drug intelligence / Profile preview

Pain-o-Joint Spray

Development stage
Unknown
Lead developer
Signature Phytochemical Industries
Modality
Small Molecules
Administration
Topical
01

Overview

Pain-o-Joint Spray is a topical fixed-dose combination analgesic spray manufactured by Signature Phytochemical Industries. It is formulated for the rapid, localized relief of musculoskeletal pain, joint pain, sprains, strains, and inflammation associated with conditions such as osteoarthritis. The spray contains four active ingredients: diclofenac diethylamine, a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis; methyl salicylate, a counterirritant that provides a warming sensation and further inhibits COX enzymes; menthol, a cooling agent that activates TRPM8 channels to distract from pain; and linseed oil, which possesses mild anti-inflammatory properties and acts as a penetration enhancer to facilitate deep absorption of the active ingredients.

Brand names
Pain O Joint SprayPain-O-Joint Spray
Other names
diclofenac + linseed oil + menthol + methyl salicylatediclofenac diethylamine + linseed oil + menthol + methyl salicylatediclofenac diethylamine, linseed oil, methyl salicylate & menthol spraydiclofenac diethylamine, linseed oil, methyl salicylate and menthol spray
02

Targets

TRPV1 (Transient receptor potential cation channel subfamily V member 1)PGHS-1 (Prostaglandin G/H Synthase 1)TRPV3 (Transient receptor potential vanilloid subtype 3)

Beyond the preview

Go deeper on Pain-o-Joint Spray.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Pain-o-Joint Spray.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call