Drug intelligence / Profile preview

pale sulfonated shale oil

Development stage
Unknown
Lead developer
Ichthyol-Gesellschaft Cordes, Hermanni & Co.
Modality
Small Molecules
Administration
Topical
01

Overview

Pale sulfonated shale oil (PSSO) is a naturally derived substance obtained from the distillation of oil-rich sedimentary rocks (shale), followed by sulfonation and neutralization. Unlike dark sulfonated shale oil, PSSO is highly purified to remove dark-colored and odorous components, making it more suitable for cosmetic and dermatological applications. It exhibits anti-inflammatory, anti-pruritic, and anti-microbial properties. It is primarily used in the treatment of inflammatory skin conditions such as atopic eczema, psoriasis, and seborrheic dermatitis. Clinical studies have demonstrated its efficacy in reducing symptoms of mild to moderate atopic eczema in children, serving as a well-tolerated alternative to topical corticosteroids.

Brand names
Ichthyol Pale
Other names
PSSOsodium shale oil sulfonateIchthyolum albicanssulfonated shale oil
02

Targets

ALOX5 (Arachidonate 5-lipoxygenase)COX

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