Drug intelligence / Profile preview

Palmex

Development stage
Unknown
Lead developer
Centro Nacional de Investigaciones Científicas
Modality
Small Molecules
Administration
Oral
01

Overview

Palmex is a natural phytotherapeutic agent and nutritional supplement developed by the Centro Nacional de Investigaciones Científicas (CNIC) in Cuba for the treatment of benign prostatic hyperplasia (BPH). It consists of a lipid extract derived from the fruits of the Cuban royal palm (*Roystonea regia*), containing a mixture of free fatty acids such as oleic, palmitic, and lauric acids. Palmex exerts its therapeutic effects through a multi-targeted mechanism, including the inhibition of the enzyme 5α-reductase (which prevents the conversion of testosterone to dihydrotestosterone), antagonism of α1-adrenoreceptors (promoting smooth muscle relaxation in the prostate and bladder neck), and antioxidant activity that reduces oxidative stress in prostate tissue. Clinical trials have demonstrated that Palmex is effective in improving lower urinary tract symptoms (LUTS), increasing maximum urinary flow, and reducing prostate volume, with a safety profile comparable to standard pharmacological treatments like finasteride and tamsulosin.

Brand names
Palmex
Other names
lipid extract of Roystonea regiaCuban royal palm fruit extract
02

Targets

SRD5A (Steroid 5-alpha-reductase)

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