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Palmitic acid-d31 (also known as [2H31] palmitate) is a stable isotope-labeled fatty acid used as a metabolic tracer in clinical research to quantify fat oxidation. In the context of the Johns Hopkins University study 'Dinner Time for Obesity and Prediabetes' (NCT03503994), this tracer is administered orally during an 'Early Dinner' intervention—defined as a meal consumed before dim light melatonin onset (DLMO). By tracking the metabolic fate of the deuterium label, researchers can assess how the timing of food intake relative to the body's endogenous circadian rhythm affects postprandial lipid metabolism and fat oxidation rates in healthy adults and those with obesity or prediabetes.
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