palmitoyl tetrapeptide-7

Palmitoyl tetrapeptide-7 is a synthetic lipopeptide composed of the amino acid sequence glycine-glutamine-proline-arginine (GQPR) attached to a palmitic acid moiety, which enhances its lipid solubility and skin penetration. It is primarily used in cosmetic and dermatological products for its anti-inflammatory and anti-aging properties. The mechanism of action involves reducing the production of interleukin 6 (IL‑6), a pro-inflammatory cytokine that accelerates collagen breakdown and skin aging. By decreasing IL‑6 levels, it helps slow down collagen degradation, reduce inflammation, promote synthesis of type I collagen, fibronectin, and hyaluronic acid, leading to improved skin elasticity and reduced appearance of wrinkles. It is often used in combination with other peptides such as palmitoyl tripeptide‑1 in formulations like Matrixyl 3000[1][2][3][4][5][6].

Other names

palmitoyl tetrapeptide-3N-palmitoylrigin