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panax ginseng + ginkgo biloba + multivitamin + polyminerals

Development stage: Unknown
Lead developer: EMS
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

This combination drug is a fixed-dose formulation consisting of two standardized botanical extracts, *Panax ginseng* and *Ginkgo biloba*, along with a comprehensive complex of multivitamins and polyminerals. It is primarily developed for the treatment of cognitive function disorders and memory deficits. *Ginkgo biloba* extract acts as a vasodilator and a platelet-activating factor (PAF) receptor antagonist, which enhances cerebral blood flow and provides neuroprotective antioxidant effects. *Panax ginseng* serves as an adaptogen that modulates the hypothalamic-pituitary-adrenal (HPA) axis and GABAergic systems to improve mental resilience and cognitive performance. The multivitamin and polymineral components provide essential micronutrients that serve as enzymatic cofactors in neuronal energy metabolism and cellular maintenance. The Brazilian pharmaceutical company EMS sponsored clinical research into this specific combination, although some trials were withdrawn before completion.

Brand names: Prince of Peace Ginkgo Biloba & Red Panax Ginseng ExtractNew Leaf Ginkgo Biloba & Korean Panax Ginseng TabletsSuperSelf Panax Ginseng with Ginkgo Biloba Extracts
Other names: panax ginseng + ginkgo biloba + multivitamin + polyminerals

Targets

PTAFR (Platelet-activating factor receptor)

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