Drug intelligence / Profile preview

panax notoginseng flower tea

Development stage
Preclinical
Lead developer
Farlong Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Panax notoginseng flower tea is an herbal therapeutic preparation derived from the inflorescence of *Panax notoginseng* (Burk.) F.H. Chen, a plant indigenous to the Yunnan province of China. Specifically developed and clinically evaluated by the Yunnan Provincial Psychiatric Hospital, the tea is utilized for its antidepressant and sedative properties. Its primary active constituents are dammarane-type triterpene saponins, most notably ginsenoside Rb3, ginsenoside Rb1, ginsenoside Rc, and various notoginsenosides. These compounds are believed to exert antidepressant effects by modulating the hypothalamic-pituitary-adrenal (HPA) axis, thereby normalizing cortisol levels, and by enhancing monoaminergic neurotransmission through the inhibition of serotonin and norepinephrine reuptake. Additionally, the tea has been shown to upregulate brain-derived neurotrophic factor (BDNF) and provide neuroprotective benefits against neuroinflammation. It is traditionally used in Chinese medicine to clear heat and calm the liver, and it is currently explored as a natural alternative or adjunct for patients with mild to moderate depression and insomnia.

Other names
Sanqi flower teaNotoginseng flower teaSanchi flower teaPseudoginseng flower teaSanqi Hua tea
02

Targets

NET (Norepinephrine Transporter)GR (Glucocorticoid receptor)SERT (Sodium-dependent serotonin transporter)BDNF (Brain-derived neurotrophic factor)

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