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Panax notoginseng Tablets

Development stage: Unknown
Lead developer: Yunnan Baiyao
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Panax notoginseng Tablets (PSQ project) is an innovative Traditional Chinese Medicine (TCM) Category 1.1 candidate developed by Yunnan Baiyao Group. Formulated as an oral tablet, the drug is derived from the roots of *Panax notoginseng* and is indicated for cardiovascular symptoms such as chest tightness, heart pain, palpitations, and dizziness caused by blood stasis in the heart veins. It is also being evaluated for the prevention of cardiovascular events in middle-aged and elderly patients. The project has completed Phase 2 clinical trials involving 704 cases and has finalized its pharmaceutical research phase.

Other names: Panax notoginseng Tablets (PSQ project)

Targets

GPIIb/IIIa (Integrin alpha-IIb/beta-3)FECH (Ferrochelatase)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)F10 (Factor Xa)PTPN1 (Protein tyrosine phosphatase 1B)TNFA (Tumor necrosis factor alpha (soluble))ER (Estrogen receptor)IL-6 (Interleukin 6)Bcl-xL (Bcl-2-like protein 1)

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