Drug intelligence / Profile preview

Pancrease MT

Development stage
Unknown
Lead developer
Johnson & Johnson
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Pancrease MT is a pancreatic enzyme replacement therapy (PERT) delivered in delayed-release capsules containing enteric-coated microtablets. It is composed of pancrelipase, a mixture of three key digestive enzymes: lipase, protease, and amylase. This medication is indicated for the treatment of exocrine pancreatic insufficiency (EPI), a condition where the pancreas does not produce enough digestive enzymes, often associated with cystic fibrosis, chronic pancreatitis, or post-pancreatectomy conditions. The enteric coating protects the enzymes from gastric acid, allowing them to be released in the duodenum where they facilitate the breakdown of fats, proteins, and starches into absorbable nutrients.

Brand names
Pancrease MTPANCREASE® MTPancrease MT 4Pancrease MT 10Pancrease MT 16Pancrease MT 20Pancrease MT 25
Other names
Pancrelipase
02

Targets

GehA (Triacylglycerol lipase GehA)AMY (Pancreatic alpha-amylase)

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